Conotoxin | 129129-65-3

Ma Conotoxins ndi gulu losiyanasiyana la poizoni ang'onoang'ono a peptide opangidwa ndi nkhono za cone (genus Conus). Nkhono za m’madzi zimenezi zimapezeka m’nyanja zotentha komanso za m’madera otentha ndipo zimadziwika ndi kusaka kwapadera. Nkhono za m'madzi zimagwiritsa ntchito utsi kuti zisamayendetse nyama zomwe zimadya, zomwe zimakhala ndi zamoyo zina zam'madzi monga nsomba ndi nyongolotsi.

Ma conotoxins amapezeka muululu wa nkhono za cone ndipo amagwira ntchito zosiyanasiyana, monga kugonjetsera nyama komanso kuteteza nyama zolusa. Ma peptides omwe ali mu conotoxins ali ndi zochitika zosiyanasiyana za mankhwala ndipo amatha kuyanjana ndi zolandilira ndi njira za ion mu dongosolo lamanjenje. Chifukwa cha kutsimikizika kwawo pazifukwa zina, ma conotoxins akopa chidwi kuchokera kwa ofufuza kuti agwiritse ntchito pazamankhwala komanso kupanga mankhwala.

Ma Conotoxins amagawidwa m'mabanja angapo kutengera kapangidwe kawo komanso zolandilira zomwe amalumikizana nazo. Mabanja ena ndi awa:

A-conotoxins: Lowetsani nicotinic acetylcholine receptors.

M-conotoxins: Tsekani njira za sodium zozungulira magetsi.

O-conotoxins: Gwirizanani ndi njira za calcium za voltage-gated.

T-conotoxins: Njira za potaziyamu zomwe zimatsata magetsi.

Poizoni izi zasonyeza kulonjeza popanga mankhwala atsopano othetsera ululu, matenda a ubongo, ndi matenda ena. Asayansi ali ndi chidwi makamaka ndi kuthekera kwawo kosintha mosankha ma receptor apadera, kuwapangitsa kukhala ofunikira pakupanga mankhwala omwe amayang'aniridwa komanso ogwira mtima.

Phukusi:25KG/BAG kapena ngati mukufuna.

Posungira:Kusunga pa mpweya wokwanira, malo ouma.

ExecutiveZokhazikika:International Standard.