Cytidine | 65-46-3

Cytidine ndi molekyulu ya nucleoside yopangidwa ndi nucleobase cytosine yolumikizidwa ndi ribose ya shuga. Ndi imodzi mwazomangamanga za RNA (ribonucleic acid) ndipo imagwira ntchito yofunika kwambiri pakupanga ma cell metabolism ndi nucleic acid synthesis.

Kapangidwe ka Mankhwala: Cytidine imakhala ndi pyrimidine nucleobase cytosine yomwe imamangiriridwa ku ribose ya shuga ya carbon 5 kupyolera mu mgwirizano wa β-N1-glycosidic.

Udindo Wachilengedwe: Cytidine ndi gawo lofunikira la RNA, pomwe limagwira ntchito ngati imodzi mwa nucleosides zinayi zomwe zimagwiritsidwa ntchito popanga zingwe za RNA panthawi yolemba. Kuphatikiza pa ntchito yake mu kaphatikizidwe ka RNA, cytidine imagwiranso ntchito m'njira zosiyanasiyana za kagayidwe kachakudya, kuphatikiza biosynthesis ya phospholipids komanso kuwongolera ma jini.

Metabolism: M'kati mwa maselo, cytidine imatha kukhala phosphorylated kupanga cytidine monophosphate (CMP), cytidine diphosphate (CDP), ndi cytidine triphosphate (CTP), zomwe ndizofunikira kwambiri pakatikati pa nucleic acid biosynthesis ndi njira zina zamankhwala.

Zakudya: Cytidine imapezeka mwachibadwa muzakudya zambiri, kuphatikizapo nyama, nsomba, mkaka, ndi masamba. Itha kupezekanso kudzera muzakudya mu mawonekedwe a cytidine okhala ndi ma nucleotides ndi ma nucleic acid.

Kuthekera Kwachirengedwe: Cytidine ndi zotuluka zake zafufuzidwa chifukwa cha ntchito zawo zochiritsira zomwe zingatheke muzochitika zosiyanasiyana zachipatala, kuphatikizapo matenda a ubongo, khansa, ndi matenda opatsirana ndi mavairasi. Mwachitsanzo, ma analogi a cytidine monga cytarabine amagwiritsidwa ntchito mu chemotherapy pochiza mitundu ina ya khansa ya m'magazi ndi lymphoma.