Honeysuckle Flower Extract 25% Chlorogenic Acid | 84603-62-3

Chotsitsa cha Honeysuckle chimachokera ku honeysuckle, yomwe imadziwikanso kuti Japan honeysuckle kapena honeysuckle. Amadziwika kuti ndi mankhwala abwino kwambiri oletsa mabakiteriya komanso ochepetsa kutupa. Awa ndi amodzi mwamankhwala odziwika bwino a zitsamba zaku China.

The Compendium of Materia Medica adautcha honeysuckle chifukwa maluwa ake poyamba amakhala oyera (siliva) kenako amasanduka achikasu (golide) akaphuka bwino. Chifukwa cha mankhwala ake apadera komanso maubwino ambiri, amagwiritsidwa ntchito osati ngati mankhwala komanso m'malo mwa tiyi chifukwa cha kukoma kwake kowawa komanso kununkhira kwake.

Kuonjezera apo, kumwa nthawi zonse sikungapweteke m'mimba, kumatha kuchepetsa kutupa pochotsa chinyezi ndi poizoni, ndipo honeysuckle ili ndi chlorogenic acid, yomwe ingachepetse chiopsezo cha gallstones.

Kuchita bwino ndi udindo wa Honeysuckle Flower Extract 25% Chlorogenic Acid: 

Chitetezo cha mtima

CGA (chlorogenic acid, CGA) monga free radical scavenger ndi antioxidant yatsimikiziridwa ndi chiwerengero chachikulu cha zoyesera ll J. Izi zamoyo za CGA zikhoza kukhala ndi chitetezo pa dongosolo la mtima.

Anti-mutagenic ndi anti-cancer zotsatira

Kuyesa kwa nyama kukuwonetsa kuti CGA ili ndi zoletsa komanso zoletsa pakupezeka kwa khansa ya m'mimba ndi khansa ya m'matumbo.

Njira zotsutsa-mutagenic ndi zotsutsana ndi khansa za CGA zikhoza kukhala zogwirizana ndi zotsatirazi: Pro-oxidation: Jiang et al. adapeza kuti CGA ndi pro-oxidant m'malo amchere, zomwe zingayambitse maselo otupa kupanga zidutswa zazikulu za DNA ndikuyambitsa kuphatikizika kwa nyukiliya. Izi zitha kukhala zogwirizana ndi hydrogen peroxide.

Lipid-kutsitsa zotsatira

Kuwongolera m'mitsempha ya CGA kunachepetsa kwambiri cholesterol ya plasma ndi triglyceride mu makoswe, komanso kuchuluka kwa triglyceride m'chiwindi.

Anti-leukemia effect

Kafukufuku wa in vitro ndi Chiang et al adapeza kuti CGA ili ndi zofooka zolimbana ndi khansa ya m'magazi J. Bandyopadhyay ndi kafukufuku wina wasonyeza kuti CGA imatha kuletsa Ber-Abl ndi c-Abl tyrosine kinase, ndikulimbikitsa apoptosis ya maselo abwino a Ber-Abl kuphatikizapo Ber. -Abl positive kuphulika lymphocytes odwala matenda myeloid khansa.

Zotsatira za Immunomodulatory

Kafukufuku wa m'galasi wasonyeza kuti CGA sichingangowonjezera kuchuluka kwa maselo a T omwe amayamba chifukwa cha ma antigen a chimfine, komanso kulimbikitsa kupanga 7-IFN ndi a-IFN mu ma lymphocytes aumunthu ndi ma leukocyte amagazi a anthu.

Hypoglycemic effect

Kafukufuku wa Andrade-Cetto A ndi Wiedenfeld H adatsimikizira kuti CGA ili ndi zotsatira za hypoglycemic mu nyama, ndipo zotsatira zake za hypoglycemic mkati mwa 3 h sizinali zosiyana ndi za glyburide [31 J. Njirayi ingakhale yokhudzana ndi kuletsa kwa glucose-6. - phosphate transferase ndi glucose mayamwidwe.

Ena

CGA imathanso kulepheretsa kupanga ma cytokines ndi chemokines omwe amayamba chifukwa cha staphylococcal exotoxin, ndikuletsa kutsika kwa fibroblast collagen network komanso kupsinjika komwe kumachitika chifukwa cha ma fibroblasts a hypertrophic scar-derived fibroblasts (mFs).

Adrenocorticotropic hormone (ACm) kukwera chifukwa cha zomwe zimachitika.