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Mafotokozedwe Akatundu:
Topicastat imakhala ndi mpikisano woletsa mphamvu pa xanthine oxidoreductase, motero imalepheretsa kupanga uric acid. Ilibe zopinga zina za pyrimidine purine metabolizing enzymes, koma mosankha zimalepheretsa Chemicalbook zotsatira pa xanthine oxidoreductase. Topicastat imakhala ndi mphamvu yoletsa kwambiri pa onse oxidized ndi kuchepetsa XOR, kotero zotsatira zake zochepetsera uric acid zimakhala zamphamvu komanso zolimba, kotero mankhwalawa angagwiritsidwe ntchito pochiza matenda aakulu a hyperuricemia mu gout.
