L-Carnitine | 541-15-1

L-carnitine, yomwe nthawi zina imatchedwa carnitine, ndi mchere wopangidwa kuchokera ku amino acid methionine ndi lysine m'chiwindi ndi impso ndipo amasungidwa mu ubongo, mtima, minofu, ndi umuna. Anthu ambiri amatulutsa michere yambiri kuti akhale athanzi. Matenda ena azachipatala, komabe, angalepheretse carnitine biosynthesis kapena kulepheretsa kugawidwa kwa maselo a minofu, monga intermittent claudication, matenda a mtima, ndi matenda ena a majini. Mankhwala ena amathanso kukhudza kwambiri carnitine metabolism m'thupi.Ntchito yaikulu ya L-carnitine ndiyo kutembenuza lipids, kapena mafuta, kukhala mafuta a mphamvu.
Makamaka, ntchito yake ndikusuntha mafuta acid mu mitochondria ya maselo a eukaryotic omwe amakhala mkati mwa nembanemba zoteteza zomwe zimazungulira ma cell. Apa, mafuta acids amalowa mu beta oxidation ndikuphwanya kupanga acetate. Chochitika ichi ndi chomwe chimayambitsa kayendedwe ka Krebs, mndandanda wa zovuta zowonongeka zamoyo zomwe ndizofunikira kuti zipereke mphamvu kwa selo lililonse m'thupi.L-carnitine imathandizanso kusunga mafupa. Tsoka ilo, mcherewu umakhala wochepa kwambiri m'mafupa pamodzi ndi osteocalcin, mapuloteni opangidwa ndi osteoblasts omwe amakhudzidwa ndi mafupa a mafupa. Ndipotu, zofookazi ndizo zifukwa zazikulu zomwe zimayambitsa matenda osteoporosis mwa amayi omwe ali ndi vuto la postmenopausal. Kafukufuku wasonyeza kuti vutoli likhoza kusinthidwa ndi L-carnitine supplementation, zomwe zimawonjezera kupezeka kwa osteocalcin.
Nkhani zina zomwe L-carnitine therapy ingathetsere zikuphatikizapo kupititsa patsogolo kugwiritsa ntchito shuga kwa odwala matenda a shuga, kuchepetsa zizindikiro zomwe zimagwirizanitsidwa ndi matenda otopa kwambiri, komanso kuyendetsa bwino chithokomiro mwa anthu omwe ali ndi hyperthyroidism. Palinso umboni wosonyeza kuti propionyl-L-carnitine ingathandize kupititsa patsogolo vuto la erectile mwa amuna, komanso kupititsa patsogolo mphamvu ya sidenafil, mankhwala ogulitsidwa pansi pa chizindikiro cha Viagra. Kuonjezera apo, kafukufuku wasonyeza kuti mcherewu umapangitsa kuti umuna ukhale wabwino komanso kuyenda.