Citrus Aurantium Extract - Synephrine

Synephrine, kapena, makamaka, p-synephrine, ndi analkaloid, imapezeka mwachibadwa mu zomera ndi zinyama zina, komanso mankhwala osavomerezeka omwe amapangidwa ndi m-substituted analog yotchedwa asneo-synephrine.p-synephrine (kapena kale Sympatol ndi oxedrine [BAN]) andm-synephrine amadziwika chifukwa cha zochita zawo za adrenergic kwautali poyerekeza ndi norepinephrine.Izi zimakhala zotsika kwambiri pazakudya zodziwika bwino monga madzi alalanje ndi zinthu zina zalalanje (mtundu wa Citrus), zonse za "zotsekemera" ndi "zowawa".Zokonzekera zomwe zimagwiritsidwa ntchito mu Traditional Chinese Medicine (TCM), yomwe imadziwikanso kuti Zhi Shi, ndi malalanje osakhwima komanso owuma ochokera ku Citrus aurantium (Fructus AurantiiImmaturus).Zotulutsa zazinthu zomwezo kapena synephrine yoyeretsedwa imagulitsidwanso ku US, nthawi zina kuphatikiza ndi caffeine, monga chowonjezera chowonjezera chochepetsa thupi kuti chigwiritsidwe ntchito pakamwa.Ngakhale kuti zokonzekera zachikhalidwe zakhala zikugwiritsidwa ntchito kwa zaka zikwi zambiri monga chigawo cha TCM-formulas, synephrine palokha si mankhwala ovomerezeka a OTC.Monga mankhwala, m-synephrine akadali ntchito ngati asympathomimetic (ie chifukwa hypertensive ndi vasoconstrictor katundu), makamaka ngati parenteral mankhwala pa matenda a mwadzidzidzi monga mantha andrarely po zochizira matenda bronchial kugwirizana ndi mphumu ndi hay-fever. .

M'mawonekedwe a thupi, synephrine ndi yopanda mtundu, yolimba ya crystalline ndipo imasungunuka m'madzi.Mapangidwe ake a maselo amachokera ku mafupa a phenethylamine, ndipo amagwirizana ndi mankhwala ena ambiri, ndi ma neurotransmitters akuluakulu epinephrine ndi norepinephrine.

Zakudya zina zowonjezera zakudya, zogulitsidwa pofuna kulimbikitsa kuchepetsa thupi kapena kupereka mphamvu, zimakhala ndi synephrine monga imodzi mwa zigawo zingapo.Nthawi zambiri, synephrine imapezeka ngati gawo lachilengedwe la Citrus aurantium ("lalanje wowawa"), womangidwa muzomera, koma amathanso kukhala opangidwa, kapena phytochemical yoyeretsedwa (ie yotengedwa kuchokera ku chomera ndikutsukidwa kukhala mankhwala. homogeneity) ., Chiwerengero cha ndende chomwe chinapezedwa ndi Santana ndi ogwira nawo ntchito muzowonjezera zisanu zosiyanasiyana zogulidwa ku US zinali pafupifupi 5 - 14 mg/g.